Lenvatinib en Cáncer Diferenciado de Tiroides: Respuestas tras la Refractariedad al Radioyodo - page 2

Survival of RAI-Refractory DTC Patients Decreases
Significantly Compared With RAI-Avid Patients
• Median survival for patients with RAI-refractory DTC and distant
metastases is estimated to be less than 3 years
1,2
Years After Metastasis Discovery
0
5
20
30
40
10
15
25
35
0.0
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
1.0
0.9
Survival
131
I uptake
No
131
I uptake
Patients are often subject to multiple complications associated with disease
progression
2
2
RAI-refractory DTC
5-year survival: < 50%
10-year survival: 10%
OS, overall survival.
Durante C, et al.
J Clin Endocrinol Metab
. 2006;91(8):2892-2899. 2. Pfister DG, Fagin JA.
J Clin Oncol
. 2008;26(29):4701-4704. 3. Brose MS, et al. Presented at
ASCO 2014. Poster 6060.
1 3,4,5,6,7,8,9,10,11,12,...27
Powered by FlippingBook