The role of PD-L1 expression as a predictive biomarker in advanced
        
        
          non-small-cell lung cancer:
        
        
          a network
        
        
          meta-analysis
        
        
          Systematic Review Aguiar Jr, Santoro, Tadokoro
        
        
          et al.
        
        
          Immunotherapy
        
        
          (2016) 8(4), 479–488
        
        
          • 13 trials with a total.
        
        
          • 1979 patients included in the current analysis
        
        
          • PD-L1 positive---652 patients.
        
        
          •
        
        
          PD-L1 negative---915 patients.
        
        
          •
        
        
          RR –13% in PD-L1-negative