 
          Clinical Case. Just one of many…
        
        
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          Clinical presentation
        
        
          – Self-detected lump in left breast
        
        
          – Core needle biopsy confirmed the presence of a 46
        
        
          mm invasive ductal carcinoma (IDC)
        
        
          – Clinical stage: T2N0M0
        
        
          – Small breasts, B cup, but patient wants a
        
        
          conservative treatment
        
        
          •
        
        
          Tumour pathology
        
        
          – IDC, grade 3
        
        
          – ER-negative, PR-negative
        
        
          – IHC 3+
        
        
          (HER2-positive)