Datos en vida real: una visión más completa de la patología - page 5

Do we need RWE?
Limitations of clinical trials
Clinical trials have high internal validity but the reproducibility of the
results in broader settings is subject of debate
Specific, but clinically significant, subsets of patients are excluded
from clinical trials
Clinical trials do not address all the clinically relevant questions
As clinical practice evolves, the results of clinical trials performed
before implementing novel therapies are unknown
1,2,3,4 6,7,8,9,10,11,12,13,14,15,...29
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