RAINBOW
Wilke H, et al. Lancet Oncol 2014
%
G1/2 G3
G4
G5 G1/2 G3
G4
G5
ASTENIA
45
12
0
0
38
5
0
0
NEUROPATÍA
38
8
0
0
32
5
0
0
DOLOR ABDOMINAL
30
6
0
0
26
3
<1
0
HTA
10
14
0
0
2
2
0
0
NEUTROPENIA
14
22
19
0
12
16
3
0
ANEMIA
26
9
0
0
26
9
<1
0
HEMORRAGIA - SANGRADO
38
4
<1
<1
16
1
<1
<1
RAMUCIRUMAB + PACLITAXEL
PACLITAXEL + PLACEBO