Limitations in predicting PAM50 intrinsic subtype and risk of
relapse score with Ki67 in estrogen receptor-positive HER2-
negative breast cancer
Fernández, Pascual et al Oncotarget, Aceptado
Ki67 IHC
Intrinsic
subtypes
0-10%
11-20%
21-30%
>30%
Luminal A
193 (81.4%)
63 (51.6%)
29 (29.3%)
9 (15.3%)
Luminal B
42 (17.7%)
59 (48.4%)
69 (69.7%)
41 (69.5%)
HER2-enriched
2 (0.8%)
0
1 (1.0%)
3 (5.1%)
Basal-like
0
0
0
6 (10.2%)