0
5
10
15
20
25
30
35
Time, months
+ Last dose
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
++
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
++
+
+
Time on therapy
Time to last scan
Bar length corresponds to treatment length.
Data cutoff date: September 30, 2016.
Time to Response and Duration of Response (PR)
(RECIST v1.1, Central Imaging Review; N = 47)
6769 – RS Herbst
Pembro
24
months
n = 47
Patients with
response, n (%)
43 (91.5)
Time to 1
st
response,
months
Median (range)
2
(2-24)
Duration of response,
months
Median (range)
NR
(2+ -
31+)
Partial response
2 months