NECITUMUMAB y avances en el tratamiento de 1ª línea carcinoma de pulmón escamoso - page 6

ONCOGENES DIANA
ALK, anaplastic lymphoma kinase;
EGFR, epidermal growth factor receptor; NSCLC, non-small cell lung cancer
1. Gerber DE et al.
Am Soc Clin Oncol Educ Book
2014:e353–65;
2. Pao W, Girard N.
Lancet Oncol
2011;12:175–80;
3. Perez-Moreno P et al.
Clin Cancer Res
2012;18:2443–51
Unknown oncogenic
drivers or oncogenic
drivers without
proven treatments
Unknown oncogenic
drivers or oncogenic
drivers without
proven treatments
EGFR M+
15–20%
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EML4-ALK+
3–7%
EGFR M+ or
EML4-ALK+
<5%
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,'*-.#'/ #$0-'
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1,2,3,4,5 7,8,9,10,11,12,13,14,15,16,...21
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