ALK y ROS-1 en CNMP: Presente y Futuro - page 8

Second-generation ALK TKIs
1. Higher specificity and potency against WT ALK
2. Higher sensitivity and potency against mutant ALK
(variable according to distinct ALK mutations)
3. Higher CNS penetration
1,2,3,4,5,6,7 9,10,11,12,13,14,15,16,17,18,...33
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