Toxicidad
Event
Axitinib (%)
Sorafenib (%)
All grade
Grade 3/4
All grade
Grade 3/4
Diarrhea
55
11
53
7
Hypertension
40
16
29
11
F i
39
11
32
5
at gue
Nausea
32
3
22
1
Vomiting
24
3
17
1
Hypothyroidism
19
<1
8
0
Stomatitis
15
1
12
<1
Hand‐foot syndrome
27
5
51
16
Rash
13
<1
32
4
Alopecia
4
0
32
0
28
*All-causality; highest AEs of interest.
Rini BI, et al. Lancet 2011
