Second‐line agents in mRCC (A–Z)
Cabozantinib
2
†
Everolimus
3
†
Axitinib
1*
Nivolumab
5 ‡
Sorafenib
6
§
Lenvatinib +
li
4
†
evero mus
1. Inlyta
®
SmPC 2016; 2. Cabometyx
®
SmPC 2016; 3. Afinitor
®
SmPC 2016; 4. Kisplyx
®
SmPC 2016; 5. Opdivo
®
SmPC 2016; 6. Nexavar
®
SmPC 2015
*
Approved in advanced RCC after sunitinib or cytokine therapy;
†
Approved in advanced RCC after prior VEGF‐targeted therapy;
‡
Approved in RCC
after prior therapy;
§
Approved as an option in first‐line advanced RCC, after IFN‐α/IL‐2 or if unsuitable for IFN‐α/IL‐2