Best reduction from baseline
        
        
          in target lesions (%)
        
        
          100
        
        
          75
        
        
          50
        
        
          25
        
        
          0
        
        
          -25
        
        
          -50
        
        
          -75
        
        
          -100
        
        
          Patients
        
        
          IPIlIMUMAB
        
        
          19%
        
        
          Best reduction from
        
        
          baseline
        
        
          in target lesions (%)
        
        
          75
        
        
          50
        
        
          25
        
        
          0
        
        
          -25
        
        
          -50
        
        
          -75
        
        
          -100
        
        
          100
        
        
          Patients
        
        
          NIVOLUMAB
        
        
          43.7%
        
        
          Best reduction from
        
        
          baseline
        
        
          in target lesions (%)
        
        
          100
        
        
          75
        
        
          50
        
        
          25
        
        
          0
        
        
          -25
        
        
          -50
        
        
          -75
        
        
          -100
        
        
          NIVO + IPI
        
        
          57.6%
        
        
          Patients
        
        
          Response to Treatment
        
        
          Wolchok at al. ASCO 2016