10 años de medicina de precisión - page 13

THE PRECISION APPROACH: TARGET EGFR
2004 2008 TIME LINE
Van Cutsem Van Cutsem Berlin Hecht Hecht
2007 2008 2006 2008 2007
Phase III II II II II
Stained ≥1% ≥1% ≥10% Strat Strat
Response rate 10% 11% 8% 4% 11%
Van Cutsem E. J Clin Oncol. 2007
Van Cutsem E. Ann Oncol 2008
Berlin J. J Clin Oncol 2006
Hecht JR. Cancer 2007
Hecht JR. ASCO-GI Meeting. 2008
Pmab
EGFR HAVE NOT PREDICTIVE
RESPONSE CAPACITY
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