Key Questions: THE BEST FIRST LINE (I)
•
The monoclonal antibodies shown to improve of clinical outcome when
combined with polichemotherapy in the first line setting (EVIDENCE LEVEL IB)
Cmab-QT
Bv-QT
ORR (ITT)
62,0%
58,0%
ORR
72,2%
63,1%
PFS
10,0 m
10,3 m
OS KRASwt 28,7 m
25.0 m
OS RASwt
33,1 m
25.0 m
P=.18
P=.017
P=.55
P=.017
P=.005
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