Key Questions: BEST CONVERSION THERAPY
•
Resection rates have been shown to be correlated with response to sistemic
therapy. (EVIDENCE LEVEL IIB)
Study
RAND
RR (%) Resection
CELIM
: FOLFOX vs FOLFIRI + Cmab
Not
70
33%
GONO
: FOLFOXIRI + Bv
Not
80
40%
OLIVIA
: Bv + FOLFOXIRI or FOLFOX YES: For QT
81 vs 62
49 vs 23%
Ye et al
. FOLFIRI or FOLFOX ± Cmab YES: For Cmab
57 vs 29
26 vs 7%
40
