THE BEGINING OF PERSONALIZED MEDICINE
2014
?
TIME LINE
MULTI-TARGET,
MULTI-DRUG
TRANSCRIPTOMIC SUBTYPES
INMUNE SUBTYPES
MULTI-TARGET
MULTI-DRUGS
CMS.1 HYPERMUTATION
INMUNOTHERAPY
CMS.4 EMT
Inmunotherapy + inh TGb + Agonist OX4
CMS 3. Metabolic desreg + KRASMUT
panRAF inh + inh metabolic
CMS2. Cuadruple WT
antiEGFR + antiIGF1 + antiERB2
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