Survival, safety, and prognostic factors for outcome with Regorafenib
        
        
          in patients with metastatic colorectal cancer refractory to standard
        
        
          therapies: results from a multicenter study (REBECCA) nested within a
        
        
          compassionate use program
        
        
          Antoine Adenis1,13*, Christelle de la Fouchardiere2, Bernard Paule3, Pascal Burtin4, David Tougeron5, Jennifer Wallet6,
        
        
          Louis-Marie Dourthe7, Pierre-Luc Etienne8, Laurent Mineur9, Stéphanie Clisant10, Jean-Marc Phelip11, Andrew Kramar6
        
        
          and Thierry Andre12