Sunitinib en
p
TNEs
G1/G2
Safety & QOL
All-causality grade 3/4 AEs in
≥4 patients in either arm
No. of patients (%)
Sunitinib (n=83)
Placebo (n=82)
Neutropenia
10 (12)
0
Hypertension
8 (10)
1 (1)
Hand–foot syndrome
5 (6)
0
Diarrhoea
4 (5)
2 (2)
Asthenia
4 (5)
3 (4)
Fatigue
4 (5)
7 (8)
Abdominal pain
4 (5)
8 (10)
Back pain
0
4 (5)
Raymond E, et al. N Eng J Med 2011
