Tratamiento del melanoma avanzado con tafinlar (DABRAFENIB) + MEKINIST (TRAMETINIB) - page 5

Cellular

Proliferation

RTK

Raf

ATP

ERK

MEK

BRAF

V600E

RAS

RESISTENCIA

BLOQUEO BRAF

ACTIVACIÓN MEK

APARICIÓN DE RESISTENCIAS EN VÍA MAPK

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