Crizotinib
Chemotherapy
Ceritinib
Alectinib
“
Old
” approach
“
New
” approach
How will we sequence ALK inhibitors in future?
Crizotinib
Chemotherapy
“
Classical
” approach
Crizotinib
“
beyond the progression
Crizotinib
Brigatinib
Indolent disease
Crizo
Oligometastatic diseases
local therapy + Crizo
Oligometastic CNS
RT + Crizo
Sistemic/symptomatic disease
A
B
INDICACIÓN NO APROBADA, EN INVESTIGACIÓN
INDICACIÓN NO APROBADA, EN INVESTIGACIÓN