NOAH: EFS (HER2-positive population)
1.00
0.75
0.50
0.25
0
0
6
12
18
24
30
36
42
Probability of EFS
Months
H + CTx
CTx
Events
36
52
3-year
EFS
70.1
53.3
HR
0.56
95% CI
0.36–0.85
p value*
0.006
Median follow-up 3 years
*Unadjusted for stratification variables: adjusted HR=0.55, p=0.0062
EFS = event-free survival; CTx = chemotherapy
Gianni, et al. Lancet 2010