MBC therapeutic goals
Prolongation of survival (OS)
Alleviation of symptoms
Maintenance or improvement in
QoL (toxicity)
Delay disease progression
(ORR, CBR and TTP/PFS)
Cure??
(oligometastatic disease)
Smith I Sem in Oncol 2006 & Chung et al The Oncologist 2003 & Cardoso et al Ann Oncol 2014;
Chung et al Oncologist 2003; Wilson et al Lancet 2015
“Cancer treatment aims to enable patients to live longer and better lives than they would without
treatment”
BALANCE
Re-Biopsy
