CHAARTED – Updated OS analysis
DOC+P is only registered for the treatment of patients with hormone-
refractory metastatic PCa
Sweeney CJ, et al. Ann Oncol 2016;27 (suppl 6): abstract 720
High volume
Low volume
ADT+DOC
ADT alone
ADT+DOC
ADT alone
ADT+DOC (median OS 51.2 mo)
ADT+DOC (median OS 58.3 mo)
ADT alone (median OS, 59.8 mo)
ADT alone (median OS 34.4 mo)
1.0
0.8
0.6
0.4
0.2
0.0
12
24
36
48
60
72
84
96 108
1.0
0.8
0.6
0.4
0.2
0.0
12
24
36
48
60
72
84
96
108
HR = 0.86
(95% CI: 0.52-
1.42)
P
=0.55
HR = 0.63
(95% CI: 0.50-
0.79)
P
<0.0001
SAEU.CAB.16.07.0040j
