Inmunoterapia + Quimioterapia
* Chemotherapy may have several immunological effects:
- Reducing nº and activity of suppressive immune cells
- Inducing immunogenic cell death
- Enhancing presentation of tumor antigens
- Inducing maduration and activation of dendritic cells
- Enhancing effector T-cell function
* Chemotherapy can induce PD-L1 expression on tumor cells
Apoteh L, et al. Ann Oncol 2015
Feng J, et al. Cancer Res 2015
Zhang P, et al. Cancer Scl 2016
