Ceritinib
(n=189)
Chemotherapy
(n=187)
ORR (CR+PR), n (%)
[95% CI]
137 (72.5)
[65.5, 78.7]
50 (26.7)
[20.5, 33.7]
CR, n (%)
1 (0.5)
0
PR, n (%)
136 (72.0)
50 (26.7)
SD, n (%)
23 (12.3)
*
88 (47.1)
†
PD, n (%)
19 (10.1)
26 (13.9)
UNK, n (%)
10 (5.3)
23 (12.3)
Median time to first
response (in responders),
weeks (range)
6.1
(5.1- 61.7)
13.4
(5.1-90.1)
G De Castro et al. WCLC 2016
Duration of response: 23,9 vs 11,1 months
1L CERITINIB: ASCEND-4
