AURA 3, AEs
AE any*, n (%)
Osimertinib (n=279)
Platinum-pemetrexed
(n=136)
Any AE
273 (98)
135 (99)
Any AE Grade ≥3
63 (23)
64 (47)
Any AE leading to death
4 (1)
1 (1)
Any serious AE
50 (18)
35 (26)
Any AE leading to discontinuation
19 (7)
14 (10)
AE, possibly causally related
#
, n (%)
Any AE
231 (83)
121 (89)
Any AE Grade ≥3
16 (6)
46 (34)
Any AE leading to death
1 (<1)
1 (1)
Any serious AE
8 (3)
17 (13)
Any AE leading to discontinuation
10 (4)
12 (9)
Papadimitrakopoulou VA, et al. WCLC 2016