Cambio de paradigma en el EGFR mutado: desde las primeras mutaciones a las de resistencia - page 25

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For pts with AR to EGFR-TKI, plasma genotyping has high sensitivity for

EGFR T790M mutations (70%)

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Plasma T790M+ status predicts for high RR and prolonged PFS on

osimertinib

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Plasma T790M negative status cannot fully replace a tumour biopsy

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