Panitumumab. en las nuevas guías de CCRm - page 12

BRAF: FACTOR
PRONÓSTICO
2. Clancy C, Burke JP, Kalady MF, Coffey JC. BRAF mutation is associated with distinct clinicopathological
characteristics in colorectal cancer: a systematic review and meta-analysis. Colorectal Dis 2013;15:e711-718
BRAF: FACTOR PRONOSTICO
:
• 21 estudios, 9885 ptes
• B-RAF-localización proximal (OR, 5.22; 95% CI, 3.80– 7.17; P < .001),
• T4 tumors (OR, 1.76; 95% CI, 1.16–2.66; P = .007),
• Y POBREMENTE DIFERENCIADOS(OR, 3.82; 95% CI, 2.71–5.36; P < .001).
1...,2,3,4,5,6,7,8,9,10,11 13,14,15,16,17,18,19,20,21,22,...47
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