METANÁLISIS DE anti EGFR
RESECCIONES (WT
KRAS
, LLD)
•
Petrelli F, Barni S. Int J Colorectal Dis 2012;27:997
‒
1004.
•
Meta-analysis indicates EGFR inhibitors increase R0 resection rate
by 60% in mCRC patients with unresectable LLD
43
72
0
20
40
60
80
Proportion (%)
Response rate
CTx alone
P = 0.0001
CTx +
EGFR mAb
11
18
0
5
10
15
20
Proportion (%)
R0 resection rate
CT alone
P = 0.04
CTx +
EGFR mAb