Panitumumab. en las nuevas guías de CCRm - page 22

METANÁLISIS DE anti EGFR
RESECCIONES (WT
KRAS
, LLD)
Petrelli F, Barni S. Int J Colorectal Dis 2012;27:997
1004.
Meta-analysis indicates EGFR inhibitors increase R0 resection rate
by 60% in mCRC patients with unresectable LLD
43
72
0
20
40
60
80
Proportion (%)
Response rate
CTx alone
P = 0.0001
CTx +
EGFR mAb
11
18
0
5
10
15
20
Proportion (%)
R0 resection rate
CT alone
P = 0.04
CTx +
EGFR mAb
1...,12,13,14,15,16,17,18,19,20,21 23,24,25,26,27,28,29,30,31,32,...47
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