Chemotherapy in NSCLC,
what has happened in the last 20 years?
•
No extensive investigation into CT agents
Scagliotti GV et al
. Phase III study comparing cisplatin plus
gemcitabine with cisplatin plus pemetrexed in chemotherapy-
naive patients with advanced-stage NSCLC.
J Clin Oncol 2008
Socinski MA et al
. Weekly nab-paclitaxel in combination with
carboplatin versus solvent-based paclitaxel plus carboplatin as
first-line therapy in patients with advanced NSCLC: final results
of a phase III trial.
J Clin Oncol 2012
•
Advances in precision medicine and immunotherapy have
led to fewer patients receiving CT