Cleopatra: Final OS Analysis
Median follow-up 50 months (range 0–70 months)
ITT population. Stratified by geographic region and neo/adjuvant chemotherapy.
CI, confidence interval; Pla, placebo; Ptz, pertuzumab.
27
OS (%)
0
10
20
30
40
50
60
70
80
90
100
0
10
20
30
40
50
70
60
Time (months)
HR 0.68
95% CI = 0.56, 0.84
p = 0.0002
Ptz + T + D
Pla + T + D
1
28
104
226
268
318
371
0
23
91
179
230
289
350
n at risk
Ptz + T + D
Pla + T + D
402
406
40.8
months
56.5
months
Δ 15.7
months
Swain S, NEJM 2015
