Disease Burden: What are we confronting?
17.439 m3.654 w
Year 5
NMIBC: 86%–98%
MIBC: 30%–63%
mBC: 9-15%
5-year survival
Muscle-Invasive Bladder
Cancer
Non-Muscle Invasive
Bladder Cancer
~70% of cases at
diagnosis
~4% of cases at
diagnosis
~25% of cases at
diagnosis
Classification
Incidence
2
Metastatic Bladder Cancer
31%–78% NMIBC will recur
10%–20% NMIBC will progress
20%–70% MIBC recur
50% MIBC will progress
American Cancer Society. Bladder Cancer. Detailed Guide.
. ;Burger M et al
. Eur Urol
. 2013;63:234-241.;Cancer Research UK. Invasive and
advanced bladder cancer stages.
org/ about-cancer/type/bladder-cancer/treatment/bladder-cancer-stage-and-grade#What.; Kaufman DS et al.
Lancet
. 2009;374(9685):239-249. 7. Gartrell BA
