Pathological Complete Response in Breast
(ypT0/is)
NeoSphere
H, trastuzumab; P, pertuzumab; T, docetaxel
p values from Cochran-Mantel-Haenszel test and adjusted for multiplicity
p=0.0198
TH
THP
HP
TP
p=0.0141
50
40
30
20
10
0
pCR, %
95% CI
p=0.003
29.0
45.8
16.8
24.0
N=107
N=107
N=107
N=96
Gianni L. et al. Lancet Oncol 2012