Hazard Ratio
95% CI
PFS (B vs. A)
0.69
[0.34, 1.40]
DFS (B vs. A)
0.60
[0.28, 1.27]
DFS (pCR vs. non-pCR)
0.68
[0.36, 1.26]
•
In NEOSPHERE, PFS and DFS results are consistent with the primary
endpoint pCR
•
PFS and DFS were pre-specified secondary endpoints and were
not powered for statistical comparisons
The definition of PFS in NEOSPHERE is the same as is commonly used for
event-free survival (EFS).
NEOSPHERE PFS, DFS Results (Nov. 2014)
NeoSphere
