 
          pCR in breast and lymph nodal status
        
        
          NeoSphere
        
        
          TH
        
        
          (n=107)
        
        
          THP
        
        
          (n=107)
        
        
          HP
        
        
          (n=107)
        
        
          TP
        
        
          (n=96)
        
        
          pCR in the breast, %
        
        
          29.0
        
        
          45.8
        
        
          16.8
        
        
          24.0
        
        
          pCR and N- at surgery, %
        
        
          21.5
        
        
          39.3
        
        
          11.2
        
        
          17.7
        
        
          pCR and N+ at surgery, %
        
        
          7.5
        
        
          6.5
        
        
          5.6
        
        
          6.3
        
        
          pCR, pathological complete response; N, node
        
        
          H, trastuzumab; P, pertuzumab; T, docetaxel
        
        
          Gianni L. et al.  Lancet Oncol 2012