PALOMA-1: Palbociclib plus letrozole improves PFS
compared to letrozole alone (ITT)
Finn RS, et al. Lancet Oncol 2015;16:25–35
90
80
70
60
50
40
30
20
10
0
0
4
8
12
16
20
24
28
32
36
40
100
Time (months)
PFS probability (%)
Palbociclib + letrozole (n=84)
Letrozole (n=81)
HR 0.488
P=0.0004
10.2 months
20.2 months
