El tratamiento con quimioterapia hoy en pacientes HER2 negativo: el papel de la eribulina - page 24

Study 301: Overall Survival
*Stratified log-rank test based on Geographical regions Her2 status by the Clinical Database.
Trt 1 554 512 450 381 332 264 217 184 150 122
87
49
36
25
15
10
5
2
Trt 2 548 484 413 353 288 236 194 165 132 111
72
41
29
21
13
10
2
1
0
100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1800
1.0
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0.0
Time (days)
No. of subjects at risk:
Median OS
(months)
Eribulin (N=554)
15.9
Capecitabine (N=548)
14.5
HR
0.879
95% CI
0.770, 1.003
p-value*
0.0560
ITT Population
Survival Distribution Function
CI = confidence interval; IVRS=interactive voice response system.
1...,14,15,16,17,18,19,20,21,22,23 25,26,27,28,29,30,31,32,33,34,...43
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