El tratamiento con quimioterapia hoy en pacientes HER2 negativo: el papel de la eribulina - page 20

Study 305: EMBRACE
Updated OS analysis
Analysis occurred at 589 events (deaths), representing 77% of the ITT population
*Nominal P value from stratified log-rank test
CI = confidence interval; HR = hazard ratio; ITT = intent-to-treat; OS = overall survival; TPC = treatment of physician’s choice
Cortes J, O’Shaughnessy J et al.
Lancet
.
2011;377:914–923
;
Twelves C, Loesch D et al.
San Antonio Breast Cancer Symposium.
2010;Poster P6-14-18
Median OS, months
Eribulin (n=508)
13.2
TPC (n=254)
10.5
HR
0.81
95% CI
0.67, 0.96
P value*
0.014
1...,10,11,12,13,14,15,16,17,18,19 21,22,23,24,25,26,27,28,29,30,...43
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