Study 301: Progression Free Survival,
Independent Review
Trt 1
554 356 229 133 88 61 44 29 26 23 17 16 12 12
8
8
8
6
5
1
1
1
0
Trt 2
548 329 220 121 89 66 47 33 28 21 19 15 14
9
8
5
3
2
2
2
1
0
0
0
2
4
6
8
10 12
16 18 20 22 24 26 28 30
1.0
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.0
PFS Distribution Function
Time (months)
0.1
No. of subjects at risk:
Stratified log-rank test: P=0.3045
ITT population – Independent Review
CI = confidence interval; HR = hazard ratio.
Median PFS
(months)
Eribulin (N=554)
4.1
Capecitabine (N=548)
4.2
HR
1.079
95% CI
0.932, 1.250
P value*
0.3045
14
32
36
34
38 40 42 44
