Revisión datos de PANITUMUMAB en función de la localización del tumor - page 5

Right colon (%)
Molecular pathways/tumour classification models
Distribution of CMS groups varies by colorectal tumour location
Guinney J, et al. Nat Med 2015;21:1350‒6 (and Supplementary Figure 10).
Right colon = caecum to transverse colon;
left colon = splenic flexure to sigmoid colon (n = 2651).
CMS1
CMS2
CMS3
CMS4
31
26
19
24
Left colon
(%)
CMS1 tumours were frequently
diagnosed in females with
right-sided lesions
CMS2 tumours were mainly
left-sided
Left colorectum (%)
Colon
Rectum
7
56
10
27
3
51
15
31
1,2,3,4 6,7,8,9,10,11,12,13,14,15,...42
Powered by FlippingBook