Revisión datos de PANITUMUMAB en función de la localización del tumor - page 7

Reference
Right/left colon
HR (95% CI)
Bae 2013
200/292
1.28 (0.95‒1.72)
Otani 2012
91/116
0.66 (0.37‒1.17)
Derwinger 2011
825/733
1.12 (1.00‒1.26)
Tentes 2010
109/186
0.89 (0.60‒1.32)
Suttie 2010
234/257
1.16 (0.97‒1.38)
Benedix 2010
8276/9329
1.12 (1.02‒1.24)
Wray 2009
48,101/34,825
1.22 (1.20‒1.24)
Deschoolmeester 2008
228
1.61 (1.01‒2.58)
Burton 2006
133/103
0.99 (0.61‒1.62)
Sinicrope 2006
286/242
0.81 (0.60‒1.09)
Krajewska 2005
106
0.38 (0.15‒0.97)
Shepherd 1971
124/191
1.35 (1.03‒1.78)
Tumour location and survival
Hazard ratios for OS favour left-
Vs right-sidedcolon cancer
Yahagi M, et al. J Gastrointest Surg 2016;20:648‒55.
Data are from a meta-analysis of 15 studies that assessed the prognostic value of colon cancer
tumour location. Right = caecum, ascending and transverse colon;
Left-sided colon cancer was significantly associated with better OS
vs right-sided (HR = 1.14; 95% CI, 1.06‒1.22; P < 0.01)
0.05
0.25
1.00
4.00
RE Model
I
2
= 41.82%
1.14 (1.06‒1.22)
Worse survival for right
Worse survival for left
1,2,3,4,5,6 8,9,10,11,12,13,14,15,16,17,...42
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