Prior CNS radiation
Prior radiotherapy was not predictive for response to
alectinib
Gadgeel, et al. J Clin Oncol 2016 34(34): 4079–85
Gadgeel, et al. WCLC 2015 (Abs. ORAL33.05)
Best intracranial response
(patients with measurable CNS disease at baseline)
70
50
-100
-90
-80
-70
-60
-50
-40
-30
-20
-10
0
10
20
30
Sum of longest diameter,
max. decrease from baseline (%)
60
40
Patients
Yes (n=34)
No (n=16)
INDICACIÓN NO APROBADA, EN INVESTIGACIÓN
